Supermicro PCIe GPU Servers for AI and Visual Computing

Complete Flexibility for AI and Visual Computing
Supermicro offers broad range of systems optimized for latest PCIe GPUs ideal for AI-enabled enterprise applications, including the new NVIDIA RTX PRO™ 6000 Blackwell Server Edition and NVIDIA H200 NVL to provide powerful and cost-effective multi-workload acceleration for large language model (LLM) inference and fine-tuning, visualization, graphics & rendering, and virtualization.
These include NVIDIA Certified systems which guarantee compatibility and support for NVIDIA AI Enterprise software to simplify the process of developing and deploying production AI.
Supermicro’s thermally-optimized architectures maximize performance in air-cooled environments and are also designed to support NVIDIA SuperNICs such as BlueField®-3 and ConnectX®7 for the best infrastructure scaling and GPU clustering with NVIDIA Quantum InfiniBand and Spectrum Ethernet.
Unleash New Possibilities with Supermicro Systems and NVIDIA PCIe GPUs
Wide-Ranging Workload Support
Highly flexible systems which can be adapted to almost any application including financial services, retail, cloud compute, virtualization, and 3D media creation. GPUs supporting NVIDIA Multi Instance GPU (MIG) allow up to four separate instances on a single card for enhanced utilization in shared environments.
Acceleration from Data Center to Edge
Broad portfolio of form factors with drop-in support and thermally-optimized architectures to provide powerful acceleration in a range of environments. From rack-scale GPU-optimized systems to data center rackmounts and compact edge systems, Supermicro offers an extensive range of systems to support any enterprise AI workload.
Open, Optimized Architectures
Utilizing the industry-standard PCIe interconnect, have also been designed for maximum thermal performance in air-cooled environments so that the latest and most powerful GPU cards can be supported at high ambient temperatures.
Multi-Accelerator Support for a Range of Workloads From the Data Center to the Edge
Match Supermicro servers with a wide selection of NVIDIA PCIe accelerators for workload-specific optimization of AI inference & fine-tuning, visual computing, agentic & physical AI, scientific simulation, virtualization, and media & design

Generative and Agentic AI
Multi-workload acceleration for AI, graphics, and media make NVIDIA GPUs the premier platforms for multi-modal generative AI pipelines.

LLM Inference and Fine-Tuning
Accelerate training, fine tuning, and inference workloads with powerful throughput and floating-point performance to build and deploy state-of-the-art AI models.

Rendering and 3D Graphics
Running professional 3D visualization applications with NVIDIA GPUs enables creative professionals to iterate more, render faster, and unlock tremendous performance advantages that increase productivity and speed up project completion.

Virtualization
Leverage NVIDIA Multi-Instance GPU (MIG) with time-slicing to create multiple GPU instances using a single accelerator, significantly increasing utilization in virtualized and cloud computing environments.
Unleash New Possibilities with Supermicro Servers and NVIDIA PCIe GPU
Wide Selection of NVIDIA PCIe GPU





Supermicro PCIe GPU Servers for Enterprise AI
Supermicro Servers: Built for AI Workload-Optimized Performance

Scalable 4U/5U Servers
Supermicro’s 4U and 5U GPU systems are engineered for high-throughput, multi-GPU performance across demanding AI, HPC, and media workloads.
The 5U SYS-522GA-NRT and AS -5126GS-TNRT2 dual-processor systems are thermally-optimized to support up to 10 double-width GPUs, as well as high-speed networking via NVIDIA BlueField®-3 DPUs and ConnectX®-7 NICs— ideal for AI inference, fine-tuning, simulation, and cloud gaming. Similarly, the 4U SYS-422GL-NR is based on the modular NVIDIA RTX PRO Server design which is optimized for enterprise AI factories, capable of supporting up to 8 double-width GPUs in 4U to accelerate a wide range of enterprise workloads—from agentic AI and LLM inference to industrial AI and digital twins.
In the future, this 4U design will also support the new NVIDIA PCIe switch board with ConnextX-8 to accelerate workloads that require significant GPU-GPU connectivity across systems. These systems use standard rackmount chassis with onboard storage and redundant power supplies, enabling seamless integration into existing data center environments and scalable deployment of GPU accelerated infrastructure.
High-Density Servers
Supermicro’s SuperBlade® multi-node platform is optimized for GPU-intensive workloads that demand both high density and scalability—such as professional rendering, industrial simulation, and digital twin applications. Available in 6U and 8U enclosures, supporting up to 20 hot-swappable GPU nodes.
SuperBlade can be configured with NVIDIA RTX™ PRO 6000 Blackwell GPUs, enabling up to 120 GPUs per rack to deliver exceptional throughout and efficiency. By integrating shared, redundant components—including advanced cooling, networking, power supplies, and centralized chassis management—SuperBlade dramatically reduces data center footprint while maximizing rack-level GPU utilization. This system design fits seamlessly into existing environments, making it ideal for enterprises looking to scale real-time ray tracing, immersive content creation, CAE/CFD workloads, and AI training pipelines.
Designed specifically for workloads that benefit from RTX-class compute, SuperBlade empowers organizations to accelerate design cycle, enhance visual fidelity, and streamline production across large-scale AI-powered pipelines.


A+ Workstations and SuperWorkstations
Supermicro’s professional workstation portfolio includes both rackmount and tower systems designed for high-performance visualization, virtualization, rendering, and AI assisted creative workflows.
The 2U rackmount AS -2115HV-TNRT can support up to four dual-width GPUs—ideal for centralized content creation, simulation, and enterprise AI development in secure, managed environments.
For desktop deployments, the SYS 532AW-C and AS -531AW-TC mid-towers are optimized for RTX PRO 6000 Blackwell Workstation Edition and Max-Q GPUs, delivering powerful performance with thermal optimization for workstation form factors.
IoT SuperServers
Supermicro’s edge-optimized and compact form-factor servers, including the SYS-E403 14B-FRN2T Box PC and the high-density SYS-212GB-NR, are purpose-built for deployment in remote or space-constrained environments. These systems are engineered with features like front-accessible power and I/O, and support for low-power GPUs to ensure reliable operation in telecom, retail, manufacturing, and other settings with distributed infrastructure.
The SYS-E403-14B-FRN2T offers a fan-based, front-access design in a compact form factor that is ideal for retail AI applications, while the MGX-based SYS 212GB-NR supports up to four NVIDIA RTX PRO 6000 Blackwell GPUs—delivering powerful AI inference in a cost-effective single-processor 2U form factor.
Together, they represent Supermicro’s ability to deliver scalable, GPU-accelerated computing with integrated networking, storage, and compute in edge-friendly footprints.
